Start patients with renal impairment on one-fourth to one-half the usual starting dose depending on the degree of impairment. Patients with renal impairment should be closely monitored during dose titration see CLINICAL PHARMACOLOGY. Maternal toxicity (decreased food consumption and body weight gain) was also noted at the two highest doses tested. Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioid-induced respiratory depression in the neonate. DILAUDID INJECTION is not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate.
Serious, life-threatening, or fatal respiratory mescaline benefits depression may occur with use of DILAUDID Oral Solution and DILAUDID Tablets. Monitor for respiratory depression, especially during initiation of DILAUDID Oral Solution or DILAUDID Tablets or following a dose increase see WARNINGS AND PRECAUTIONS. After a few weeks of use, patients may develop both tolerance and physical dependence on Dilaudid and may need to be slowly weaned off the drug to avoid withdrawal symptoms. Ask your doctor or pharmacist if you should have naloxone available to treat opioid overdose. Teach your family or household members about the signs of an opioid overdose and how to treat it. Do not increase your dose, take the medication more often, or take it for a longer time than prescribed.
Symptoms of overdose may include the following:
Do not take more of it or take it more often than prescribed by your doctor. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use Dilaudid for a condition for can alcoholism cause narcissism which it was not prescribed. Do not give Dilaudid to other people, even if they have the same symptoms you have. You can ask your healthcare provider or pharmacist for information about Dilaudid that was written for healthcare professionals.
- To lower your risk, your doctor should have you use the smallest dose of hydromorphone that works, and use it for the shortest possible time.
- Avoid the use of DILAUDID INJECTION in patients with circulatory shock.
- These effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain.
- Opioids can cause sleep-related breathing disorders including central sleep apnea (CSA) and sleep-related hypoxemia.
Generic Name(S): hydromorphone
These can include breathing problems, low blood pressure, extreme drowsiness, and coma. Fatal side effects can occur if you use opioid medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing. Pregnant rats were treated with hydromorphone hydrochloride from Gestation Day 6 to 17 via oral gavage doses of 1, 5, or 10 mg/kg/day (0.4, 2, or 4 times the HDD of 24 mg based on body surface area, respectively). Maternal toxicity was noted in all treatment groups (reduced food consumption and body weights in the two highest dose groups). There was no evidence of malformations or embryotoxicity reported. Inform patients that the use of DILAUDID INJECTION, even when taken as recommended, can result in addiction, abuse, and misuse, which can lead to overdose and death see WARNINGS AND PRECAUTIONS.
Additional doses may be given every 2 to 3 minutes, if symptoms return before medical help arrives. The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is used with other products that may what is a drinker’s nose also cause drowsiness or breathing problems. The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also cause drowsiness or breathing problems. Patients with moderate hepatic impairment should be started at one-fourth to one-half the recommended starting dose and closely monitored during dose titration.
How to take hydromorphone
Misuse is the intentional use, for therapeutic purposes, of a drug by an individual in a way other than prescribed by a healthcare provider or for whom it was not prescribed. Since Dilaudid is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Keep track of the amount of medicine used from each new bottle.
The risk is increased with concurrent abuse of DILAUDID INJECTION with alcohol and/or other CNS depressants. Abuse of and addiction to opioids in some individuals may not be accompanied by concurrent tolerance and symptoms of physical dependence. In addition, abuse of opioids can occur in the absence of addiction. The pharmacokinetics of hydromorphone are affected by hepatic impairment.
If the decision is made to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In patients already receiving an opioid analgesic, prescribe a lower initial dose of the benzodiazepine or other CNS depressant than indicated in the absence of an opioid, and titrate based on clinical response. If an opioid analgesic is initiated in a patient already taking a benzodiazepine or other CNS depressant, prescribe a lower initial dose of the opioid analgesic, and titrate based on clinical response.
Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. If you swallow broken, chewed, crushed, or dissolved tablets you may receive too much hydromorphone at once instead of receiving the medication slowly over time. Drinking alcohol can increase your risk of side effects from this drug.